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Active AHCY, human recombinant protein

SAHH, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, Adenosyl Homocysteinase

Product info
Primary Accession P23526
Concentration 5
Calculated MW 52.1 kDa (1-432 aa + N-terminal polyhistidine tag). In the native form the protein exists in the tetrameric form and this form is required for activity.
Additional Info
Gene ID 191
Gene Symbol AHCY
Other Names SAHH, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, Adenosyl Homocysteinase
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Results BioVision’s Active AHCY has been tested for its activity using Adenosyl Homocysteinase (AHCY) Activity Fluorometric Assay Kit (K807-100). It has a specific activity of >350 mU/mg.
Target/Specificity AHCY/SAHH
Format Liquid
Storage -80°C; 5 mg/ml in 50 mM potassium phosphate, 1 mM EDTA, pH 7.2 containing 20% glycerol.
Citations (0)

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AHCY (EC is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AHCY controls the intracellular S-adenosylhomocysteine (SAH) concentration that is crucial for transmethylation reactions. AHCY deficiency causes hypermethioninemia. The recombinant human AHCY produced in E.Coli is a single, non-glycosylated polypeptide chain and is purified by proprietary chromatographic techniques.


Coulter-Karis D.E.,et al.Ann. Hum. Genet. 53:169-175(1989).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 195.00
$ 395.00
$ 4,995.00
Cat# PBV11139r-10
Availability: 5-7days
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