|Calculated MW||31.9 kDa|
|Other Names||2310046B19Rik, AW561899, cI-35, CMG-2, CMG2,|
|Sequence||QAQEQPSCKK AFDLYFVLDK SGSVANNWIE IYNFVHQLTE RFVSPEMRLS FIVFSSQATI ILPLTGDRYK IGKGLEDLKA VKPVGETYIH EGLKLANEQI QNAGGLKASS IIIALTDGKL DGLVPSYAEN EAKKSRSLGA SVYCVGVLDF EQAQLERIAD SKDQVFPVKG GFQALKGIIN SILAQSCTEI LELSPSSVCV GEKFQVVLTG RAVTSISHDG SVLCTFTANS TYTKSEKPVS IQPSSILCPA PVLNKDGETL EVSISYNDGK SAVSRSLTIT ATECTNGLEH HHHHH|
|Storage||-20°C;In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.|
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ANTXR2, also known as anthrax toxin receptor 2, is a widely expressed anthrax toxin receptor family protein. The main functional domain of this protein is an extracellular integrinlike von Willebrand factor type A (VWA) domain with a metal ion dependent adhesion site, through which it adheres selectively to collagen type IV and laminin. This protein and the related protein ATR/TEM8 serve as receptors for the protective antigen of Bacillus anthracis. Recombinant mouse ANTXR2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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