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>   home   >   Products   >   Proteins   >   Glyoxalase II (Glx II), Human Recombinant   

Glyoxalase II (Glx II), Human Recombinant

Hydroxyacylglutathione hydrolase, mitochondrial, HAGH1, GLO2

Product info
Primary Accession Q16775
Calculated MW 32.4 kDa
Additional Info
Gene ID 3029
Other Names Hydroxyacylglutathione hydrolase, mitochondrial, HAGH1, GLO2
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE;≥90%
Recombinant Yes
Target/Specificity HAGH
Format Liquid
Storage -20°C;30% glycerol, 50 mM Tris pH 7.4 and 150 mM NaCl
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The glyoxalase system consists of Glyoxalase I (Glx I) and Glyoxalase II (Glx II) which is responsible for detoxifying α-ketoaldehydes such as the potent and cytotoxic methylglyoxal (MG). Glx I converts MG to S-D-lactoyl-glutathione (SLG). SLG is then hydrolyzed to D-lactate and reduced glutathione by Glx II. Glx II desensitizes cells to p53-dependent DNA damage-induced apoptosis. It also plays a role during development and in the pathogenesis of cancer and neurodegenerative diseases. Glyoxalase II may also be important in the regulation of spermatogenesis.

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$ 295.00
$ 1,325.00
Cat# PBV11552r-10
Availability: 5-7days
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