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Human Inosine-5′-Monophosphate Dehydrogenase II, human recombinant

IMP dehydrogenase type II, IMPDH II, IMPD2, IMPDH

Product info
Primary Accession P12268
Calculated MW 57 kDa
Additional Info
Gene ID 3615
Other Names IMP dehydrogenase type II, IMPDH II, IMPD2, IMPDH
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE;> 90%
Recombinant Yes
Target/Specificity IMPDH2
Format Liquid
Storage -20°C;20 mM Tris, pH 8.0, 150 mM NaCl, 2mM DTT, 2mM EDTA and 20% glycerol
Citations (0)

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Inosine monophosphate dehydrogenase, IMPDH, (E.C. is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis and it is essential for lymphocyte proliferation. IMPDH oxidizes inosine 5’-monophosphate (IMP) to xanthine 5’-monophosphate (XMP) using NAD as a cofactor. It plays a critical role in cell growth and in the malignancy of some tumors. IMPDH II is the predominant isoform of IMPDH and is specifically linked to a wide range of cancers and lymphocyte proliferation. BioVision’s active human IMPDH II is suitable for functional assays, high-throughput screening and preclinical studies in drug discovery.

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$ 195.00
$ 645.00
Cat# PBV11611r-20
Availability: 5-7days
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