Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Proteins   >   rat CNTF Protein   

rat CNTF Protein

Rat Ciliary Neurotrophic Factor, Recombinant,E. coli

  • WB - rat CNTF Protein PG10009-025
    rat_CNTF - Abgent rat CNTF differentially promotes the activation of STAT3 and ERK in adipocyte and preadipocyte 3T3 L1 cells.Cells were stimulated with increasing concentrations of rat CNTF (#PG10009) for 10 min. The cells were subjected to western blot analysis and the activation of ERK and Stat3 were determined using anti-phospho-ERK and anti-phospho-Stat3.
Product Information
Additional Information
Precautionsrat CNTF Protein is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


CNTF is a polypeptide trophic factor, member of the alpha-helical cytokine superfamily1. It was initially purified from the chick eye on the basis of its ability to promote survival of E8 chick ciliary ganglion neurons in culture2. CNTF is synthesized by glia both in the CNS and PNS3 and it has been demonstrated that CNTF is ubiquitously distributed in neurons and glia throughout the rodent brain4. CNTF effects are mediated by a tripartite receptor complex consisting of two signal-transducing subunits (leukemia inhibitory factor receptor, gp130) and a CNTF-specific ligand-binding-subunit (CNTFR)5

CNTF can support the survival of many different cell populations within the PNS and the vitro, CNTF promotes proliferation and neuronal specifications in hippocampal neurons. in vivo, CNTF supports the viability of non-primate motor neurons7, induces sprouting of cholinergic motor neurons8 and delays neural degeneration in genetic models of motor neuron disease9. In addition, it is involved in the development stage of astrocytes and oligodendocytes10


1 . Mufson, al.(1999)Prog. Neurobiol. 57,451.
2 . Adler, al.(1979)Science204,1434.
3 . Murphy, al.(1997)Prog. Neurobiol. 52,355.
4 . Henderson, J.T. et al.(1994)Mol. Brain Res. 22,151.
5 . Stahl, al. (1993) J. Biol. Chem.268, 7628.
6 . Richardson, P.M.(1994)Pharmacol. Ther. 63,187.
7 . Ip, N.Y. et al.(1991)J. Physiol. 85,123.
8 . Gurney, al.(1992)J. Neurosci. 12,3241.
9 . Sendtner, al.(1992)Nature358,502.
10 . Mayer, al.(1994)Development120,143.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 115.20
$ 181.20
$ 723.60
Cat# PG10009-025
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions