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Anti-B MyB Antibody

     
  • WB - Anti-B MyB Antibody ABO11231
    Anti-B MyB antibody, ABO11231, Western blottingRecombinant Protein Detection Source: E.coli derived -recombinant Human MYBL2, 46.8KD(162aa tag+ M1-L245)Lane 1: Recombinant Human MYBL2 Protein 10ngLane 2: Recombinant Human MYBL2 Protein 5ngLane 3: Recombinant Human MYBL2 Protein 2.5ng
  • IHC - Anti-B MyB Antibody ABO11231
    Anti-B MyB antibody, ABO11231, IHC(P)IHC(P): Rat Brain Tissue
  • WB - Anti-B MyB Antibody ABO11231
    Anti-B MyB antibody, ABO11231, Western blottingLane 1: Rat Spleen Tissue LysateLane 2: Rat Thymus Tissue LysateLane 3: Rat Brain Tissue LysateLane 4: HELA Cell LysateLane 5: COLO320 Cell LysateLane 6: MCF-7 Cell Lysate
  • ICC - Anti-B MyB Antibody ABO11231
    Anti-B MyB antibody, ABO11231, ICCICC: A549 Cell
  • IHC - Anti-B MyB Antibody ABO11231
    Anti-B MyB antibody, ABO11231, IHC(P)IHC(P): Human Tonsil Tissue
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession P10244
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Myb-related protein B(MYBL2) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 4605
Other Names Myb-related protein B, B-Myb, Myb-like protein 2, MYBL2, BMYB
Calculated MW 78764 MW KDa
Application Details Immunocytochemistry , 0.5-1 µg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5 µg/ml, Human, Rat, Mouse
Subcellular Localization Nucleus.
Protein Name Myb-related protein B
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human B MyB(1-17aa MSRRTRCEDLDELHYQD), identical to the related mouse sequence and different from the related rat sequence by two amino acids.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Contains 3 HTH myb-type DNA-binding domains.
Protein Information
Name MYBL2
Synonyms BMYB
Function Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

MYBL2(V-MYB avian myeloblastosis viral oncogene homolog-like 2), also called MYB-RELATED GENE BMYB, is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al.(1991) assigned the MYBL2 gene to chromosome Xq13. However, Noben-Trauth et al.(1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned Mybl2 in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

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$ 280.00
Cat# ABO11231
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