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Anti-Fibulin 2 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P98095 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Fibulin-2(FBLN2) detection. Tested with WB in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 2199 |
|---|---|
| Other Names | Fibulin-2, FIBL-2, FBLN2 |
| Calculated MW | 126573 MW KDa |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human, Rat, Mouse |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary. |
| Protein Name | Fibulin-2 |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Fibulin 2(188-205aa DPERHYEDPYSYDQEVAE), different from the related mouse and rat sequences by two amino acids. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the fibulin family. |
| Name | FBLN2 |
|---|---|
| Function | Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108). |
| Cellular Location | Secreted, extracellular space, extracellular matrix |
| Tissue Location | Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Fibulin-2, also known as FBLN2, is a protein that in humans is encoded by the FBLN2 gene. This gene encodes an extracellular matrix protein, which belongs to the fibulin family. By isotopic in situ hybridization, this gene is mapped to 3p25.1. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. It may play a role in testis development. Its binding to fibronectin and some other ligands is calcium dependent.
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