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Anti-CAT1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P30825 |
| Host | Rabbit |
| Reactivity | Human |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for High affinity cationic amino acid transporter 1(SLC7A1) detection. Tested with WB in Human. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 6541 |
|---|---|
| Other Names | High affinity cationic amino acid transporter 1, CAT-1, CAT1, Ecotropic retroviral leukemia receptor homolog, Ecotropic retrovirus receptor homolog, ERR, Solute carrier family 7 member 1, System Y+ basic amino acid transporter, SLC7A1, ATRC1, ERR, REC1L |
| Calculated MW | 67638 MW KDa |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human |
| Subcellular Localization | Cell membrane ; Multi-pass membrane protein . |
| Tissue Specificity | Ubiquitous. . |
| Protein Name | High affinity cationic amino acid transporter 1 |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human CAT1(613-629aa LDADQARTPDGNLDQCK), different from the related mouse and rat sequences by four amino acids. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Name | SLC7A1 (HGNC:11057) |
|---|---|
| Function | High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q09143}; Multi-pass membrane protein |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
High affinity cationic amino acid transporter 1, also called solute carrier family 7(cationic amino acid transporter, y+ system), member 1(SLC7A1) or ATRC1 is a protein that in humans is encoded by the SLC7A1 gene. This gene is mapped to 13q12.3. It acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor and plays a role in the Na+-independent y+ cationic amino acid transport system. This gene is high-affinity, low capacity permease involved in the transport of the cationic amino acids(arginine, lysine and ornithine) in non-hepatic tissues.
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