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BAK1 Antibody

Rabbit Polyclonal Antibody

  • WB - BAK1 Antibody ABV10023
    Western blot analysis of BAK1 using Jurkat cell lysate (Lane 1 & 2).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16611
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23409 Da
Additional Information
Gene ID 578
Positive Control Jurkat cell lysate
Application & Usage Western blot analysis (1-4 µg/ml) and immunoprecipitation (5-20 µg/ml).
Other Names Apoptosis regulator BAK, Bcl-2-like protein 7
Target/Specificity Bak1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) peptide affinity purified rabbit anti-Bak polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBAK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BAK1
Synonyms BAK, BCL2L7, CDN1
Function In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
Cellular Location Mitochondrion membrane; Single-pass membrane protein
Tissue Location Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle
Research Areas
Citations (0)

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Bak is a homolog of apoptosis inhibitor Bcl-2. Bak is a member of the Bcl-2 family of proteins and contains Bcl-2 homology region (BH-) 1, 2 and 3. Unlike Bcl-2, Bak promotes cell death and counteracts the anti-apoptotic effect of Bcl-2. The immunoaffinity purified antibody detects a 30 kDa band, corresponding to the expected molecular weight of Bak on SDS-PAGE immunoblots.

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$ 245.00
Cat# ABV10023
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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