|Reactivity||Human, Mouse, Rat|
|Positive Control||Mouses 3T3 cell lysate|
|Application & Usage||Western Blot analysis (1 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.|
|Formulation||200 µg (0.5 mg/ml) affinity purified rabbit anti-KLF4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||KLF4 antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
KLF4 belongs to the erythroid Kruppel-like factor (EKLF) family that is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. KLF4 can act as both a repressor and activator of transcription. KLF4 regulates the expression of key transcription factors during embryonic development and is important in maintaining embryonic stem cells. It also contributes to the down-regulation of p53/TP53 transcription.
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