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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Cathepsin L Antibody   

Cathepsin L Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07711
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 37564 Da
Additional Information
Gene ID 1514
Positive Control Western Blot: Jurkat cell lysate. IHC: Kidney tissue
Application & Usage Western blotting (0.5-4 µg/ml), and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control. Detects both the proenzyme and the mature form of cathepsin L
Other Names CTSL, CATL, CTSL1, MEP, EC
Target/Specificity Cathepsin L
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit anti-cathepsin L polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.1% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCathepsin L Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CTSL1
Function Important for the overall degradation of proteins in lysosomes.
Cellular Location Lysosome.
Research Areas
Citations (0)

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Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins s µggests that it may play a role in invasion and metastasis and could be a useful prognostic indicator for cancer.

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$ 245.00
Cat# ABV10158
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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