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BAFF Antibody

Rabbit Polyclonal Antibody

  • WB - BAFF Antibody ABV10167
    Western blot analysis of BAFF expression with Jurkat cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y275
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 31223 Da
Additional Information
Gene ID 10673
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. A 32 kDa full length BAFF and the 18 kDa cleavage fragment can be detected.
Other Names TALL-1, THANK, BLyS, TNFSF13B, TNFSF20, CD257, DTL, TALL-1, ZTNF4
Target/Specificity BAFF
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-BAFF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBAFF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T- cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines
Research Areas
Citations (0)

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BAFF (for B cell Activating Factor) is a novel member in the TNF family. BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNF-α and TRAIL, THANK was shown to activate NF-kB and c-Jun N-terminal kinase (JNK) and to induce apoptosis.

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$ 245.00
Cat# ABV10167
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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