|Reactivity||Human, Mouse, Rat|
|Calculated MW||44695 Da|
|Positive Control||Jurkat cell lysate|
|Application & Usage||The antibody can be used for Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide is available separately.|
|Other Names||Acetyl-CoA acetyltransferase mitochondrial|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-ACAT1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||ACAT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a major role in ketone body metabolism.|
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Provided below are standard protocols that you may find useful for product applications.
Acetyl-Coenzyme A acetyltransferase 1 (ACAT1) is a mitochondrial enzyme that catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A. ACAT1 may play an important role in the development of atherosclerosis due to cholesterol buildup in macrophage.
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