ACAT2 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q8CAY6 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 41298 Da |
Gene ID | 110460 |
---|---|
Positive Control | Jurkat cell lysate, rat kidney tissue lysate |
Application & Usage | The antibody can be used for Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide is available separately. |
Other Names | Acetyl-CoA acetyltransferase cytosolic |
Target/Specificity | ACAT2 |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-ACAT2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | ACAT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Acat2 |
---|---|
Function | Involved in the biosynthetic pathway of cholesterol. |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9BWD1} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acetyl-Coenzyme A acetyltransferase 2 (ACAT2) is an enzyme involved in lipid metabolism. Patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3 prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
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