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TSP1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07996
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 129383 Da
Additional Information
Gene ID 7057
Positive Control TSP-1 purified protein
Application & Usage Western blot: 1:200 (This information is only intended as a guide. The optimal dilutions must be determined by the user.)
Other Names Thrombospondin-1
Target/Specificity TSP1
Antibody Form Liquid
Appearance Colourless liquid
Formulation 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTSP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name THBS1
Synonyms TSP, TSP1
Function Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).
Cellular Location Endoplasmic reticulum. Sarcoplasmic reticulum
Research Areas
Citations (0)

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Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. It has also been used as a potential regulator of tumor growth and metastasis. TSP expression is highly regulated by different hormones and cytokines and is developmentally controlled. TSP stimulates the growth of vascular smooth muscle cells and human foreskin fibroblasts. A combination of IFN-gamma and TNF-alpha inhibits TSP production in these cells.

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$ 275.00
Cat# ABV10223
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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