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PID/MTA2 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94776
Other Accession NP_004730
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 75023 Da
Additional Information
Gene ID 9219
Application & Usage Western blotting (1 µg/ml). An approximately 75 kDa band can be detected. HeLa cell lysate can be used as a positive control. No cross-reactivity to MTA1.
Other Names MTA2 , PID, MTA1L1, MTA1-L1, DKFZp686F2281
Target/Specificity PID/MTA2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) immunopaffinity purified rabbit anti-PID/MTA2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPID/MTA2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTA2
Synonyms MTA1L1, PID
Function May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624}
Tissue Location Widely expressed.
Citations (0)

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PID/MTA2, also termed MTA1-L1, is a novel molecule that has been found to be involved in p53 pathway. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylastion of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues.

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$ 265.00
Cat# ABV10229
(40 western blots)
Availability: 5-7days
Bulk Size
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