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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   FAF1 Antibody   

FAF1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UNN5
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 73954 Da
Additional Information
Gene ID 11124
Application & Usage Western blotting (0.5-4 µg/ml) and in immunoprecipitation and Immunohistochemistry. However, the optimal conditions should be determined individually. Rat kidney cell lysate can be used as a positive control.
Other Names FAF1 (CT), Fas-associated protein 1, hFAF1, HFAF1s, TNFRSF6, TNFRSF6 associated factor 1 antibody, FAF1
Target/Specificity FAF1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-FAF1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFAF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FAF1
Synonyms UBXD12, UBXN3A
Function Potentiates but cannot initiate FAS-induced apoptosis.
Cellular Location Nucleus.
Tissue Location Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes
Research Areas
Citations (0)

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FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD, FADD, and RIP, FAF1 lacks a DDH (Death domain homologous region) and cannot induce apoptosis independent of Fas activation.

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$ 245.00
Cat# ABV10253
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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