Cathepsin F Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9UBX1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 53366 Da |
Gene ID | 8722 |
---|---|
Application & Usage | Western blotting (1:500-2000). However, the optimal conditions should be determined individually. Detects ~55 kDa cathepsin F precursor and ~35 kDa mature cathepsins F. |
Other Names | cysteine protease |
Target/Specificity | Cathepsin F |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (1 mg/ml) affinity purified rabbit anti-cathepsin F polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Cathepsin F Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CTSF |
---|---|
Function | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. |
Cellular Location | Lysosome. |
Tissue Location | High expression levels in heart, skeletal muscle, brain, testis and ovary; moderate levels in prostate, placenta, liver and colon; and no detectable expression in peripheral leukocytes and thymus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cathepsin F is a cysteine protease that plays a role in invariant chain processing and major histocompatibility complex class II peptide loading by microphages. Cathepsin F has the substrate specificity similar to that of cathepsins L and S.
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