|Calculated MW||53366 Da|
|Application & Usage||Western blotting (1:500-2000). However, the optimal conditions should be determined individually. Detects ~55 kDa cathepsin F precursor and ~35 kDa mature cathepsins F. |
|Other Names||cysteine protease|
|Formulation||100 µg (1 mg/ml) affinity purified rabbit anti-cathepsin F polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Cathepsin F Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.|
|Tissue Location||High expression levels in heart, skeletal muscle, brain, testis and ovary; moderate levels in prostate, placenta, liver and colon; and no detectable expression in peripheral leukocytes and thymus|
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Provided below are standard protocols that you may find useful for product applications.
Cathepsin F is a cysteine protease that plays a role in invariant chain processing and major histocompatibility complex class II peptide loading by microphages. Cathepsin F has the substrate specificity similar to that of cathepsins L and S.
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