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Neurexin Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q07310 |
| Reactivity | Human, Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 173994 Da |
| Gene ID | 116508 |
|---|---|
| Application & Usage | Western blotting (1:200-1000). However, the optimal concentrations should be determined individually. The antibody recognizes both alpha (~170 kDa) and beta (~50 kDa) isoforms of Neurexin in samples from human, rat, and bovine origins. Reactivity to other species has not been tested. |
| Other Names | NRXN |
| Target/Specificity | Neurexin |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µl (1 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Neurexin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Nrxn3 |
|---|---|
| Function | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling (By similarity). |
| Cellular Location | Presynaptic cell membrane {ECO:0000250|UniProtKB:Q9CS84}; Single-pass type I membrane protein |
| Tissue Location | Brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Neurexins comprise a family of neuronal cell surface proteins present primarily in the brain. Neurexins are tho µght to serve as signaling receptors and may play a role in axon guidance and synaptogenesis. The cytoplasmic tail of neurexin interacts with the synaptic vesicle protein synaptotagmin and binds to CASK, a protein with homology to the PSD95 family of synaptic junction proteins.
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