|Reactivity||Human, Rat, Bovine|
|Calculated MW||173994 Da|
|Application & Usage||Western blotting (1:200-1000). However, the optimal concentrations should be determined individually. The antibody recognizes both alpha (~170 kDa) and beta (~50 kDa) isoforms of Neurexin in samples from human, rat, and bovine origins. Reactivity to other species has not been tested.|
|Formulation||100 µl (1 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Neurexin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Secreted. Note=Some isoforms seems to be secreted|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Neurexins comprise a family of neuronal cell surface proteins present primarily in the brain. Neurexins are tho µght to serve as signaling receptors and may play a role in axon guidance and synaptogenesis. The cytoplasmic tail of neurexin interacts with the synaptic vesicle protein synaptotagmin and binds to CASK, a protein with homology to the PSD95 family of synaptic junction proteins.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.