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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Phospho-p70 S6 Kinase Antibody   

Phospho-p70 S6 Kinase Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBS0
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 53455 Da
Additional Information
Gene ID 6199
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects p70 S6 kinase only when phosphorylated at Thr389.
Other Names RPS6KB1 , p70S6k , p70 , S6K , p70(S6K)-alpha , P70S6K , p70(S6K)-alpha , p70-alpha, Ribosomal protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal protein S6 kinase 2; p70-S6K 2; P70S6K2; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; S6K-beta; p70-beta; S6 kinase-related kinase; SRK; Serine/threonine-protein kinase 14B
Target/Specificity Phospho-p70 S6 Kinase
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-Phospho-S6 (Thr389) polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPhospho-p70 S6 Kinase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS6KB2
Synonyms STK14B
Function Phosphorylates specifically ribosomal protein S6.
Cellular Location Cytoplasm. Nucleus.
Research Areas
Citations (0)

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p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. P70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5’oligopyrimidine tract mRNAs. A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the N-terminus that encode a nuclear localizing signal. Both isoforms lie on a mitogen-activated signaling pathway downstream of phosphoinositide 3 kinase (PI3K) and the target of rapamycin FRAP/mTOR, and distinct from the Ras/MAP kinase cascade.

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$ 345.00
Cat# ABV10374
(40 western blots)
Availability: 5-7days
Bulk Size
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