Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Fbx32/MAFbx/ATR-1 Antibody   

Fbx32/MAFbx/ATR-1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q91Z62
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Additional Information
Positive Control Rat kidney tissue lysate
Application & Usage Western Blot analysis (1-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.
Other Names F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein
Target/Specificity Fbx32
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-Fbx32 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFbx32/MAFbx/ATR-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Fbxo32
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q969P5}. Nucleus {ECO:0000250|UniProtKB:Q969P5}. Note=Shuttles between cytoplasm and the nucleus. {ECO:0000250|UniProtKB:Q969P5}
Tissue Location Specifically expressed in cardiac and skeletal muscle EMBL; AY059628; AAL16406.1; -; mRNA RefSeq; NP_598205.1; NM_133521.1 UniGene; Rn.72619; - ProteinModelPortal; Q91Z62; - SMR; Q91Z62; - STRING; 10116.ENSRNOP00000010361; - PaxDb; Q91Z62; - GeneID; 171043; - KEGG; rno:171043; - UCSC; RGD:620373; rat CTD; 114907; - RGD; 620373; Fbxo32 eggNOG; KOG3926; Eukaryota eggNOG; ENOG410YPWK; LUCA HOGENOM; HOG000263478; - HOVERGEN; HBG051572; - InParanoid; Q91Z62; - KO; K10305; - UniPathway; UPA00143; - PRO; PR:Q91Z62; - Proteomes; UP000002494; Unplaced GO; GO:0005737; C:cytoplasm; ISS:UniProtKB GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0000151; C:ubiquitin ligase complex; NAS:BHF-UCL GO; GO:0004842; F:ubiquitin-protein transferase activity; TAS:RGD GO; GO:0014889; P:muscle atrophy; IDA:RGD GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IMP:BHF-UCL GO; GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IGI:BHF-UCL GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB GO; GO:0014894; P:response to denervation involved in regulation of muscle adaptation; ISS:UniProtKB GO; GO:0014878; P:response to electrical stimulus involved in regulation of muscle adaptation; IDA:UniProtKB GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:RGD InterPro; IPR036047; F-box-like_dom_sf SUPFAM; SSF81383; SSF81383; 1 2: Evidence at transcript level; Complete proteome; Cytoplasm; Nucleus; Reference proteome; Ubl conjugation pathway CHAIN 1 350 F-box only protein 32 /FTId=PRO_0000119924 DOMAIN 218 266 F-box MOTIF 57 62 Nuclear localization signal MOTIF 164 168 Nuclear export signal. MOTIF 275 290 Bipartite nuclear localization signal SEQUENCE 350 AA; 40926 MW; 24AB59BC74F72472 CRC64; MPFLGQDWRS PGQSWVKTAD GWKRFLDEKS GTFVSDLSSY CNKENLFNSL NYDVAAKKRK KDIQNSKTKT QYFHQEKWIY VHKGSTKERH GYCTLGEAFN RLDFSTAILD SRRFNYVVRL LELIAKSQLT SLSGIAQKNF MNILEKVVLK VLEDQQNIRL IRELLQTLYT SLCTLVQRVG KSVLVGNINM WVYRMETTLH WQQQLNSIQI SRPAFKGLTI TDLPVCLQLN IMQRLSDGRD LVSLGQAAPD LHVLSEDRLL WKRLCQYHFS ERQIRKRLIL SDKGQLDWKK MYFKLVRCYP RREQYGVTLQ LCKHCHILSW KGTDHPCTAN NPESCSVSLS PQDFINLFKF
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Atrogin-1 (Atr1) is also known as Muscle Atrophy F-box (MAFbx). It is an E3 ubiquitin ligase that initiates ATPdependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx is approximately a 43kDa protein.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 89.00
$ 245.00
Cat# ABV10391-30
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 2,500+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions