|Reactivity||Human, Mouse, Rat|
|Calculated MW||41871 Da|
|Positive Control||Rat kidney tissue lysate|
|Application & Usage||Western Blot analysis (1-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.|
|Other Names||Peroxisomal 3-oxoacyl-CoA thiolase A|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-ACAA2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||ACAA2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Abolishes BNIP3-mediated apoptosis and mitochondrial damage.|
|Cellular Location||Mitochondrion. Note=Colocalizes with BNIP3 in the mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
ACAA2 (acetylcoenzyme A acyltransferase 2), is member of the thiolase family of enzymes and is involved in lipid metabolism. ACAA2 is localized in the mitochondria. ACCA2 catalyzes the last conversion step of acetyl-CoA to 3-oxoacyl-CoA, in the fatty acid oxidation pathway.
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