|Application ||WB, IHC, IP|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Chicken|
|Calculated MW||36791 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml), immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. The antibody detects proform (43 kDa) and the mature form (29 kDa) of cathepsin K.|
|Other Names||CTSK , CTSO2 , CTSO , CTSO1, PKND, CTS02 , PYCD , MGC23107 , EC 184.108.40.206|
|Formulation||100 µg (0.5 mg/ml) protein A purified rabbit anti-cathepsin K polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Cathepsin K Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis, protein degradation, and apoptosis. Cathepsin K expression is highest in bone, cartilage, and skeletal muscle.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.