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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   HDAC10 Antibody   

HDAC10 Antibody

Rabbit Polyclonal Antibody

  • WB - HDAC10 Antibody ABV10455
    Western blot analysis of HDAC10 expression. Lane 1: Jurkat Cells;Lane 2: Mouse Intestine;Lane 3: Rat Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969S8
Other Accession AAL30513
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 71445 Da
Additional Information
Gene ID 83933
Application & Usage Western blotting (0.5-4 µg/ml), However, the optimal concentrations should be determined individually. The antibody recognizes 74 kDa HDAC-10 of human, mouse, and rat origins. A 55 kDa cleavage fragment can also be detected in mouse and rat tissue lysates.
Other Names HD10 , Histone deacetylase 10
Target/Specificity HDAC10
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHDAC10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HDAC10
Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Cellular Location Cytoplasm. Nucleus. Note=Excluded from the nucleoli
Tissue Location Ubiquitous. High expression in liver, spleen, pancreas and kidney
Research Areas
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HDAC family are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns. These results s µggest that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

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$ 265.00
Cat# ABV10455
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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