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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   HDAC11 Antibody   

HDAC11 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96DB2
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 39183 Da
Additional Information
Gene ID 79885
Application & Usage Western blotting (0.5-4 µg/ml), However, the optimal concentrations should be determined individually. The antibody recognizes 39 kDa HDAC-11 of human, mouse, and rat origins
Other Names HD11 , Histone deacetylase 11
Target/Specificity HDAC11
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHDAC11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HDAC11
Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Cellular Location Nucleus. Note=Predominantly nuclear.
Tissue Location Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis
Research Areas
Citations (0)

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HDAC family are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns. These results s µggest that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

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$ 285.00
Cat# ABV10456
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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