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E-Selectin Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IP |
|---|---|
| Primary Accession | P16581 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 66655 Da |
| Gene ID | 6401 |
|---|---|
| Application & Usage | Western blotting (0.5-4 µg/ml) , Immunohistochemistry (paraffin, 10-20 µg/ml) and immunoprecipitation (10-20 µg/ml). However, the optimal conditions should be determined individually. |
| Other Names | SELE , LECAM2 , ESEL , ELAM , ELAM-1 , CD62E , ELAM1 |
| Target/Specificity | E-Selectin |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5mg/ml) protein A purified rabbit anti-E-Selectin polyclonal antibody in phosphate-buffered saline (PBS) containing 0.02% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | E-Selectin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SELE |
|---|---|
| Synonyms | ELAM1 |
| Function | Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Selectins are a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. E-Selectin (also called ELMA-1, CD62E) expressed on endothelial cells. L-Selectin (also called LECAM-1) is expressed on the majority of B and naïve T cells and on most monocytes, neurophils and eosinophils. P-Selectin (also called GMP-140) expressed on activated platelets and endothelial cells. Selectins interact with specific carbohydrates expressed by activated endothelial cells, monocytes, and neutrophils.
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