Bcl-Rambo Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P59017 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46719 Da |
Gene ID | 94044 |
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Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~56 kDa band in samples from human, mouse and rat origins. Reactivity to other species has not been tested. |
Other Names | BCL2L13 , Q9BXK5 , BCL-RAMBO , MIL1 |
Target/Specificity | BCL2L13 |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.2mg/ml) affinity purified rabbit anti-Bcl-rambo polyclonal antibody in phosphate-buffered saline (PBS) containing 0.1% BSA, 30% glycerol, and 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Bcl-Rambo Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Bcl2l13 |
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Synonyms | Mil1 |
Function | May promote the activation of caspase-3 and apoptosis. |
Cellular Location | Mitochondrion membrane; Single-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Bcl-rambo shares the common structural characteristics with other members of the anti-apoptotic Bcl-2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence proceeds the membrance anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that it membrane anchor C-terminus region is responsible for its apoptotic activity, not its Bcl-2 homology motifs.
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