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Bin1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O08539
Other Accession BC065160
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 64470 Da
Additional Information
Gene ID 30948
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Other applications have not been tested. The antibody recognizes ~65 kDa band in samples from human, mouse and rat origins. A cleavage fragment (~45 kDa) can also be detected in apoptotic samples. Reactivity to other species has not been tested.
Other Names BIN1 , AMPH2 , amphiphysin-like , MGC10367 , DKFZp547F068 , AMPHL , SH3P9
Target/Specificity Bin1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2mg/ml) immunoaffinity purified rabbit anti-Bin-1 polyclonal antibody in phosphate-buffered saline (PBS) containing 0.1% BSA, 30% glycerol, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBin1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Bin1
Synonyms Amphl, Sh3p9
Function May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.
Cellular Location Cytoplasm. Nucleus
Tissue Location Isoform 1 is expressed mainly in the brain. Isoform 2 is widely expressed
Research Areas
Citations (0)

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BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly thro µgh activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.

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$ 245.00
Cat# ABV10508
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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