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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   BIK Antibody   

BIK Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13323
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 18016 Da
Additional Information
Gene ID 638
Application & Usage Western blotting (2-6 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as positive controls. The antibody detects a ~17 kDa BIK in samples from human, mouse, and rat origins. A ~15 kDa cleavage fragment can also be detected
Other Names BCL2 interacting killer, Apoptosis inducer NBK, BIP 1, BIP, bik
Target/Specificity BIK
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) Protein A affinity purified rabbit anti-BIK polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBIK Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BIK
Synonyms NBK
Function Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
Cellular Location Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Around the nuclear envelope, and in cytoplasmic membranes
Research Areas
Citations (0)

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BIK is a member of Pro-apoptotic Bcl-2 family proteins. Altho µgh Bik lacks Bcl-2 homologus region, BH1 and BH2, BIK interacts with Bcl-2 and Bcl-xL. BIK has been shown to induce apoptosis by activating caspase-9.

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$ 245.00
Cat# ABV10536
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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