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RBP4 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P02753 |
| Other Accession | NP_006735 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Goat IgG |
| Calculated MW | 23010 Da |
| Gene ID | 5950 |
|---|---|
| Application & Usage | Western blotting (1:500-1:1000). However, the optimal concentrations should be determined individually. Recombinant human RBP4 can be used as a positive control. The antibody recognizes ~25 kDa human RBP4. Reactivity to other species has not been tested. |
| Other Names | Retinol binding protein 4 |
| Target/Specificity | RBP4 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µl affinity purified goat polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | RBP4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RBP4 |
|---|---|
| Function | Retinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (PubMed:22665496). |
| Cellular Location | Secreted |
| Tissue Location | Detected in blood plasma and in urine (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
RBP4 (Retinol Binding Protein 4). Retinol is transported in blood bound to the carrier protein RBP. Under physiological conditions, RBP binds transthyretin (TTR) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The RBP/TTR molar ration provides an indirect way to indicate marginal vitamin A deficiency.
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