|Calculated MW||23010 Da|
|Application & Usage||Western blotting (1:500-1:1000). However, the optimal concentrations should be determined individually. Recombinant human RBP4 can be used as a positive control. The antibody recognizes ~25 kDa human RBP4. Reactivity to other species has not been tested.|
|Other Names||Retinol binding protein 4|
|Formulation||100 µl affinity purified goat polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||RBP4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.|
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Provided below are standard protocols that you may find useful for product applications.
RBP4 (Retinol Binding Protein 4). Retinol is transported in blood bound to the carrier protein RBP. Under physiological conditions, RBP binds transthyretin (TTR) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The RBP/TTR molar ration provides an indirect way to indicate marginal vitamin A deficiency.
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