|Reactivity||Human, Mouse, Rat|
|Calculated MW||26734 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~28 kDa KLK12 with rat kidney tissue lysate and 16 kDa KLK12 isoform with Jurkat and 3T3 cell lysates on SDS-PAGE immunoblots.|
|Other Names||KLKL5 , KLK-L5 , MGC42603 , DKFZp686H1078|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Kallikrein 12 (KLK12) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The human KLK gene family encodes about 15 serine proteases and has the potential to serve as cancer biomarkers. The Kallikrein 12 (KLK 12) is one the KLK members located on chromosome 19. Different splice variants of the KLK12 produces three transcript variants encoding different isoforms that can be found on amino acid 254, 248 and 110.
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