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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SLK Antibody   

SLK Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H2G2
Other Accession NP_055535.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 142695 Da
Additional Information
Gene ID 9748
Application & Usage Western blotting (1:500 – 1:2500) and immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the SLK of human and mouse origin. Reactivity to other species has not been tested.
Other Names SLK, STE20-like Kinase, SLK, Sucrose nonfermenting like kinase, STK2, Serine/Threonine Kinase 2
Target/Specificity SLK
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSLK Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLK
Synonyms KIAA0204, STK2
Function Mediates apoptosis and actin stress fiber dissolution.
Cellular Location Cytoplasm.
Tissue Location Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle
Research Areas
Citations (0)

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SLK (STE20-like kinase), also known as STK2 (serine/threonine protein kinase 2) or se20-9, is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.

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$ 245.00
Cat# ABV10569-100
Availability: 5-7days
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