AAK1 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q2M218 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 76094 Da |
Gene ID | 57232 |
---|---|
Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~95 kDa AAK1 in samples from human, mouse and rat origins. Reactivity to other species has not been tested. |
Other Names | AAK-1, AAK1, AKK 1, AP2 associated kinase 1, Adaptor associated kinase 1 |
Target/Specificity | AAK1 |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | AAK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZNF630 |
---|---|
Function | May be involved in transcriptional regulation. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
AAK1 is a serine/threonine kinase that is tho µght to coordinate the recruitment of AP-2 to receptors containing tyrosine-based internalization motifs by phosphorylating the µ2 subunit. There is strong evidence that this protein is the endogenous mu 2 kinase and plays a regulatory role in clathrin-mediated endocytosis, including the regulation of fatty acid synthesis and cholesterol synthesis.
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