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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   GPVI Antibody   

GPVI Antibody

Rabbit Polyclonal Antibody

  • WB - GPVI Antibody ABV10632
    Western blot analysis of GPVI expression in Jurkat cell lysate (Lane 1, 2).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HCN6
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36866 Da
Additional Information
Gene ID 51206
Application & Usage Western blotting (0.5-4). However, the optimal conditions should be determined individually. The antibody recognizes ~58 kDa human GPVI. Jurkat cell lysate can be used as a positive control.
Other Names Glycoprotein VI , glycoprotein 6, GP6 , gp6, gp 6, platelet collagen receptor
Target/Specificity GPV
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsGPVI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GP6
Function Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.
Cellular Location Isoform 1: Cell membrane; Single-pass membrane protein
Tissue Location Megakaryocytes and platelets.
Research Areas
Citations (0)

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Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity and the formation of thrombin and fibrin.

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$ 245.00
Cat# ABV10632
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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