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Calbindin-D-28K Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P12658 |
| Other Accession | EDL05596 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29994 Da |
| Gene ID | 12307 |
|---|---|
| Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~28 kDa Calbindin- D-28K of human, mouse, rat, and monkey origins. Reactivity to other species has not been tested. |
| Other Names | CALB, CALB1, RTVL-H protein, calbindin 1, calbindin 1 |
| Target/Specificity | Calbindin |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-Calbindin-D-28K polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Calbindin-D-28K Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Calb1 |
|---|---|
| Function | Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. |
| Tissue Location | Expressed in the modiolar nerve root and in bushy neurons in the ventral cochlear nucleus (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calbindin-D-28K (also known as vitamin D-dependant calcium binding protein) belongs to a family of low molecular weight calcium-binding proteins (CaBPs). Calbindin-D-28K is found mostly in subpopulations of central and peripheral nervous system nuerons and also in certain epithelial cells involved in Ca2+ transport.
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