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TLR10 Antibody

Rabbit Polyclonal Antibody

  • WB - TLR10 Antibody ABV10720
    Western blot analysis of TLR10 expression in Jurkat cell lysate (Lane 1& 2).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BXR5
Other Accession BAF84715
Reactivity Human, Mouse, Rat, Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 94564 Da
Additional Information
Gene ID 81793
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~75 kDa and 94 kDa isoforms of TLR10 in Jurkat cell lysate. Reactivity to other species has not been tested.
Other Names Toll-like receptor 10
Target/Specificity TLR10
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTLR10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLR10
Function Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines
Research Areas
Citations (0)

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The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is homologous to TLRs 1 and 6 and is highly expressed in the lymphoid tissues.

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$ 245.00
Cat# ABV10720
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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