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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HMG-CoA Reductase Antibody   

HMG-CoA Reductase Antibody

Rabbit Polyclonal Antibody

  • WB - HMG-CoA Reductase Antibody ABV10740
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04035
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 97476 Da
Additional Information
Gene ID 3156
Positive Control Jurkat cell lysate, HeLa cell lysate
Application & Usage The antibody can be used for Western blotting (0.5–4 µg/ml).
Other Names hydroxymethylglutaryl-CoA reductase
Target/Specificity AMPK⍺1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-HMG-CoA Reductase polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHMG-CoA Reductase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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HMG-CoA reductase (HMGCR) is the rate-limiting enzyme for cholesterol biosynthesis. HMGCR is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from the product of the reductase reaction. Statin, a class of cholesterol-lowering dr µgs inhibits HMGCR by lowering plasma cholesterol.

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$ 265.00
Cat# ABV10740
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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