|Calculated MW||21227 Da|
|Positive Control||Recombinant human CT-1|
|Application & Usage||Western Blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human CT-1 can be used as a positive control.|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human CT-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||CT-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.|
|Tissue Location||Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Human Cardiotrophin-1 (CT-1) is a member of the leukemia inhibitory/ciliary neurotrophic factor/Oncostatin M/interleukin-6/interleukin-11 family of cytokines. Cardiotrophin-1 affects cells thro µgh interaction with the gp 130 receptor subunit. Recombinant human Cardiotrophin-1 is a 22.5 kDa protein containing 200 amino acid residues.
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