|Application ||WB, E|
|Positive Control||3 PEG Conjugates (20 kDa, 5 kDa, 10 kDa)|
|Other Names||Polyethylene Glycol|
|Formulation||1 mg/ml in TBS, pH 9.0|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Anti- PEG Antibody (Clone 26A04) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Polyethylene Glycol (PEG) is a polymer of ethylene oxide available in size variants from 400 Da to 40 kDa. It is nonionic, nontoxic, biocompatible, strong, and hydrophilic and has a large exclusion volume in aqueous solution. PEG has a number of industrial and biomedical applications. The modification of a biopharmaceutical with PEG increases its hydrodynamic radius, reduces immunogenicity and proteolytic cleavage. In particular, therapeutic proteins are conj µgated with PEG to slow down their clearance from circulation and improve bioavailability. PEG antibodies can be a vital tool for propelling therapeutics to market by serving as a positive control anti-dr µg antibody, measuring clearance of a dr µg, or simply as a QA release confirming PEGylation.
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