|Calculated MW||10732 Da|
|Application & Usage||Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually.|
|Other Names||Eotaxin; C-C motif chemokine 11; Full=Small-inducible cytokine A11; Eosinophil chemotactic protein|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-mouse eotaxin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Eotaxin/CCL11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.|
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Provided below are standard protocols that you may find useful for product applications.
Eotaxin is a 74-amino acid eosinophil-chemotactic CC chemokine originally found in bronchoalveolar lavage fluid from allergic inflammatory subjects. It is involved in regulating the recruitment and activation of inflammatory leukocytes, particularly eosinophils. It may play a fundamental role in the development of allergic responses.
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