Eotaxin/CCL11 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P51671 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 10732 Da |
Gene ID | 6356 |
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Application & Usage | Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. |
Other Names | Eotaxin; C-C motif chemokine 11; Full=Small-inducible cytokine A11; Eosinophil chemotactic protein |
Target/Specificity | Eotaxin |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-mouse eotaxin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Eotaxin/CCL11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCL11 |
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Synonyms | SCYA11 |
Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions (PubMed:8597956). Binds to CCR3 (PubMed:8631813). |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Eotaxin is a 74-amino acid eosinophil-chemotactic CC chemokine originally found in bronchoalveolar lavage fluid from allergic inflammatory subjects. It is involved in regulating the recruitment and activation of inflammatory leukocytes, particularly eosinophils. It may play a fundamental role in the development of allergic responses.
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