|Calculated MW||26416 Da|
|Application & Usage||Western blot analysis (0.5-4 µg/ml). Recombinant human flt3-Ligand can be used as a positive control. However, the optimal conditions should be determined individually.|
|Other Names||SL cytokine; Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human flt3-Ligand polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Flt3 Ligand Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.|
|Cellular Location||Isoform 1: Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Human flt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells. The antibody was produced using the recombinant human flt3-ligand as immunogen, which is a soluble 17.6 kDa polypeptide containing 155 amino acid residues, that comprises the extracellular domain of the transmembrane flt3-ligand protein.
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