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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RANKL Antibody   

RANKL Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14788
Other Accession BAB71768
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35478 Da
Additional Information
Gene ID 8600
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human sRANK Ligand can be used as a positive control.
Other Names RANK Ligand, RANKLigand, Receptor activator of nuclear factor kappa B ligand, TNF-related activation-induced cytokine, Osteoprotegerin ligand
Target/Specificity RANKL
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-hsRANKL polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsRANKL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFSF11
Function Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Cellular Location Isoform 1: Cell membrane; Single-pass type II membrane protein Isoform 2: Cytoplasm.
Tissue Location Highest in the peripheral lymph nodes, weak in spleen, peripheral blood Leukocytes, bone marrow, heart, placenta, skeletal muscle, stomach and thyroid
Research Areas
Citations (0)

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Human RANK (receptor activator of NF-kB) is a member of the TNFR family, identified as a dentritic cell membrane protein. Human soluble RANK Ligand is a soluble 20 kDa polypeptide, comprising the TNF homologous region of RANKL (176 amino acid residues).

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$ 245.00
Cat# ABV10919
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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