|Calculated MW||14208 Da|
|Application & Usage||The antibody can be used in Western Blot analysis (0.5-4 µg/ml). Recombinant human FABP-1 can be used as a positive control.|
|Other Names||Fatty acid-binding protein liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP-1, FABP1|
|Formulation||200 µg (0.5 mg/ml) affinity purified rabbit anti-human FABP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||FABP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850). Binds cholesterol (PubMed:25732850). Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Human Fatty Acid Binding Protein-s exhibit high affinity for small lipophilic ligands. Studies s µggest that FABPs are involved in the uptake and metabolism of fatty acids, maintenance of cellular membrane fatty acids levels, intracellular trafficking, modulation of specific enzymes of lipid metabolic pathways, as well as in the modulation of cell growth and differentiation.
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