|Calculated MW||14208 Da|
|Application & Usage||Western blot analysis (0.5-4 µg/ml). Per researchers feedback, it can also be used in neutralization (3-6 µg/ml). However, the optimal conditions should be determined individually.|
|Other Names||FABP, FABP-3, FABP 3, Fatty acid-binding protein, mammary-derived growth inhibitor|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human FABP3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.55 BSA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||FABP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850). Binds cholesterol (PubMed:25732850). Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).|
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Human Fatty Acid Binding Protein-3 (FABP-3) exhibits high affinity for small lipophilic ligands. Studies s µggest that FABPs are involved in the uptake and metabolism of fatty acids, maintenance of cellular membrane fatty acids levels, intracellular trafficking, modulation of specific enzymes of lipid metabolic pathways, as well as in the modulation of cell growth and differentiation.
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