|Calculated MW||15164 Da|
|Positive Control||Recombinant human FABP-5|
|Application & Usage||Western Blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human FABP-5 can be used as a positive control.|
|Other Names||Epidermal-type fatty acid-binding protein, E-FABP, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human FABP5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||FABP5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.|
|Tissue Location||Keratinocytes; highly expressed in psoriatic skin|
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Provided below are standard protocols that you may find useful for product applications.
FABPs have been reported to be involved in the uptake and metabolism of fatty acids, maintenance of cellular membrane fatty acids levels, intracellular trafficking, modulation of specific enzymes of lipid metabolic pathways, as well as in the modulation of cell growth and differentiation.
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