FGF-19 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O95750 |
Other Accession | NP_005108.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 24003 Da |
Gene ID | 9965 |
---|---|
Application & Usage | Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human FGF-19 can be used as a positive control. |
Other Names | FGF19, FGF-19, FGF 19, Fibroblast growth factor 19; FGF-19; FGF19, FGF 19 |
Target/Specificity | FGF-19 |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-human FGF-19 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | FGF-19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FGF19 |
---|---|
Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
Cellular Location | Secreted. |
Tissue Location | Expressed in fetal brain, cartilage, retina, and adult gall bladder. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Fibroblast Growth Factor-19 (FGF-19) is a high affinity heparin dependent ligand for FGFR4. Human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.