|Application ||WB, E|
|Calculated MW||24003 Da|
|Application & Usage||Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human FGF-19 can be used as a positive control.|
|Other Names||FGF19, FGF-19, FGF 19, Fibroblast growth factor 19; FGF-19; FGF19, FGF 19|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human FGF-19 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||FGF-19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.|
|Tissue Location||Expressed in fetal brain, cartilage, retina, and adult gall bladder.|
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Provided below are standard protocols that you may find useful for product applications.
Fibroblast Growth Factor-19 (FGF-19) is a high affinity heparin dependent ligand for FGFR4. Human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.
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