|Calculated MW||46950 Da|
|Application & Usage||Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human BMP-12 can be used as positive control.|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human BMP-12 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||BMP-12 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play an active role in the motor area of the primate neocortex.|
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Provided below are standard protocols that you may find useful for product applications.
BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation.
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