|Calculated MW||51737 Da|
|Positive Control||Recombinant human BMP-5|
|Application & Usage||The antibody can be used in Western Blot analysis (0.5-4 µg/ml). It detects monomer, dimer and trimer of BMP-5.|
|Other Names||Bone morphogenetic protein 5, BMP-5|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human BMP-5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||BMP-5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces cartilage and bone formation.|
|Tissue Location||Expressed in the lung and liver.|
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Provided below are standard protocols that you may find useful for product applications.
BMPs (bone morphogenetic proteins) belong to the TGF-βsuperfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Active human BMP-5 is a 31 kDa homodimeric protein consisting of two 134 amino acid polypeptide chains.
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