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TCR alpha Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6ISU1
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 29266 Da
Additional Information
Gene ID 171558
Application & Usage Western blotting (0.5-4 µg/ml). Based on researcher’s feedback, it can also be used in immunoprecipitation (10-20 µg/ml); and Immunohistochemistry (15-25 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes TCR α in human sample, and to a lesser extent to mouse and rat samples. Jurkat cell lysate can be used as a positive control.
Other Names T cell antigen receptor, T cell receptor alpha, TCRA, TCRD
Target/Specificity TCRa
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTCR alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow
Research Areas
Citations (0)

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TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either α and β or γ and δ chains. The vast majority of circulating T cells (95%) express the α/β heterodimer while ro µghly 2-5% express the γ/δ heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction thro µgh the TCR.

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$ 265.00
Cat# ABV11031
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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