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BMP-2 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q00888 |
| Other Accession | EAX10387 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47113 Da |
| Gene ID | 5672 |
|---|---|
| Application & Usage | Western blotting (0.5-2 µg/ml). It detects the 14 kDa monomer, 28 kDa dimer, as well as the 58 kDa tetramer of human BMP-2. Recombinant human BMP-2 can be used as a positive control. Reactivity to other species has not been tested. |
| Other Names | BMP2, BMP-2, BMP 2, bone morphogenetic protein 2, BMP-2A, BMP2A , BMP 2A |
| Target/Specificity | BMP-2 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-BMP-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | BMP-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PSG4 |
|---|---|
| Synonyms | CGM4, PSG9 |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented thro µghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis. It is also expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary and small intestine.
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